Rejuran Healer vs. Rejuran HB+: How Do They Differ, and How Many Sessions?

Rejuran Healer is a product focused solely on PN, while Rejuran HB+ blends PN with hyaluronic acid at a 1:1 ratio and adds the anesthetic lidocaine.
Because the ingredients differ, our guidance on recommended intervals, when you can start washing your face, and how quickly bumps settle also differs. The right choice depends on whether firmness and overall skin quality come first, or dryness and injection discomfort, and the number of sessions is set accordingly.
Ingredients in the Two Products
- PN (polynucleotide): A basic building block of DNA, derived from salmon. Injected into the dermis, it helps create an environment in which damaged skin can recover and works to enhance the skin's own regenerative capacity. It is contained in both products.
- Hyaluronic acid: Contained only in Rejuran HB+, at a 1:1 ratio with PN. It helps the skin retain moisture.
- Lidocaine: A local anesthetic contained in Rejuran HB+ that helps reduce the stinging sensation during injection.
REJURAN Healer vs. REJURAN HB+
| Category | Rejuran Healer | Rejuran HB+ |
|---|---|---|
| Preparation and Treatment Time | About 15–30 minutes after numbing cream | About 15~30 minutes after self-cleansing and numbing cream |
| Anesthesia | Numbing Cream | Numbing cream; the product contains lidocaine |
| Bumps | Usually subsides within 1~3 days, along with injection marks | Eases within 2~3 hours; 1~2 days depending on skin condition |
| Face washing and makeup | From 2–3 hours after treatment | From the next day |
| Bruising and Swelling | Usually eases within 1~2 weeks | Mild and eases soon |
| Recommended interval and number of sessions | 3 sessions at 3–4 week intervals, then maintenance treatments | At least 3 sessions at 2–3 week intervals |
Changes Seen Over Repeated Sessions
- Elasticity and a clearer tone: Healer uses PN alone to steadily support a recovery environment for damaged skin, with elasticity and tone addressed over repeated sessions.
- Hydration: HB+ addresses regeneration and hydration at the same time.
- Texture and fine lines: HB+ works to address skin tone, texture, pores and fine lines together.
Choosing by Skin Concern
1. Skin that feels lax due to loss of elasticity
- Recommended product: Rejuran Healer 2cc
- Recommended interval: every 3–4 weeks
- Recommended sessions: 3, followed by maintenance depending on skin condition
- Characteristics: Considered when looking at full-face anti-aging together with a clearer skin tone.
2. Skin with both dryness and loss of elasticity
- Recommended product: REJURAN HB+ 1cc
- Recommended interval: every 2–3 weeks
- Recommended number of sessions: at least 3
- Characteristics: Considered when you wish to address both regeneration and hydration of damaged skin.
3. If pain from previous injection treatments was a concern
- Recommended product: REJURAN HB+
- Characteristics: In addition to numbing cream, the lidocaine in the product takes effect. How much you feel varies with the area, skin thickness and your skin condition on the day.
4. If you have plans on the evening of treatment
- Characteristics: When you may resume cleansing and makeup differs between the two products, so if you have plans that day, please let us know in advance during your consultation.
There is also an option to deliver 2cc of either product using DermaShine, a negative-pressure injection device. A comparison of types including REJURAN Scar is provided separately.
View REJURAN types: Healer, HB+ and Scar compared
Procedure order
The treatment proceeds in the order of personalized consultation, numbing cream, disinfection, treatment and finishing care; for HB+ only, self-cleansing is added before the numbing cream. With both products, you can return to your normal routine right after treatment.

Precautions on the Day of Treatment (The Most Important 24 Hours)
- Cleansing and makeup may be resumed 2~3 hours later for Healer, and from the next day for HB+.
- Do not rub or massage the injection sites firmly.
What to Avoid for One Week
- Avoid heavy drinking, smoking and hot baths for 3~7 days after treatment, and refrain from saunas, jjimjilbang and strenuous exercise for the same period.
- For HB+, avoid vigorous massage and meridian massage for one month.
Aftercare
- Moisturize and apply sun protection generously.
- Schedule your next session according to each product's interval, adjusting based on your skin's response each time.
- Because PN is derived from salmon, please tell us before treatment if you have a fish or seafood allergy; and because HB+ contains lidocaine, if you have an allergy to anesthetics. Please also let us know in advance about pregnancy or breastfeeding, inflammation or wounds in the treatment area, or blood-thinning medication.
- If swelling and redness do not subside but worsen, if you develop a fever or increasing pain, or if you feel a hard lump, please contact us immediately.
Booking and consultation
Face Filter Clinic Suwon offers 1-session and 3-session plans based on REJURAN Healer 2cc and REJURAN HB+ 1cc. During your personalized consultation, we look together at whether dryness or elasticity is your primary concern and how much injection pain concerns you, then choose which product and how many sessions.
This content is provided as general treatment information and is not a substitute for diagnosis or treatment. Always consult a medical professional to decide whether and how to proceed with a treatment.